‏إظهار الرسائل ذات التسميات Surgery. إظهار كافة الرسائل
‏إظهار الرسائل ذات التسميات Surgery. إظهار كافة الرسائل

الثلاثاء، 8 فبراير 2011

Abdominal and groin hernias

Definition:
  • the protrusion of an organ or any other body structure outside the wall of its normal containing cavity
Classification:
  • hernias can be classified by:
    • their anatomical location
    • whether they are congenital or acquired
    • structures involved
  • several subclassification systems exist for groin hernias
Risk factors:
  • age
  • male sex
  • obesity
  • chronic cough
  • heavy lifting
  • prostatism
  • chronic constipation
Clinical presentation:
  • patients may present with symptomatic or asymptomatic hernias

Alarm features?

  • assessment should rule out incarceration or strangulation as these are surgical emergencies requiring urgent referral
  • signs and symptoms of strangulation include:
    • irreducible mass which is firm, painful, and tender (erythema over mass in later stages)
    • signs of bowel obstruction
    • fever
    • raised white blood cell (WBC) count
    If these alarm symptoms are present >> Refer urgently to
    surgeon

    Clinical presentation

    These can present as different hernia types including:
    • Richter's hernia:
      • only a portion of the circumference of the bowel is included in the sac, hence strangulation without obstruction may occur
      • reduction of an unrecognised Richter's hernia is potentially dangerous as it could lead to perforation and peritonitis
      • they are most common in femoral hernias 
    • Littre's hernia: 
      • Meckel's diverticulum within hernial sac
      • may be associated with delayed small bowel obstruction symptoms and signs 
    • Sliding hernia:
      • also known as hernie-en-glissade
      • retroperitoneal structures and posterior parietal peritoneum slip through the hernial orifice
      • no attempt to dissect the hernia from the sac should be made as blood supply to the viscera may be compromised

         

        Epigastric hernia

        Epigastric hernia is a hernia through the linea alba between the xiphisternum and umbilicus (commonly midway between the two):
        • hernia content is usually extraperitoneal fat 
        • the hernial neck may be narrow and can strangulate
        • this hernia may lead to symptoms quite out of proportion to its size
        • differential diagnosis of divarication of the recti muscles and intra-abdominal pathology must be ruled out
        • repaired by excision or reduction of the protruding extraperitoneal fat and/or peritoneal sac
        • the defect is closed with a simple or Mayo technique with a non-absorbable suture or mesh repair
        • repair may also involve resection of ischaemic tissue

        Incisional hernia

        • incisional hernias develop at a point of weakness in a previous abdominal wound
        • pain is usually located over the abdominal wall defect which may be exacerbated by straining maneuvers
        • patients may describe changes in bowel habits
        • early surgical referral is recommended for hernias at increased risk or incarceration or strangulation
        Epidemiology:
        • estimated occurrence is 3-13% following primary abdominal incisions
        • recurrence rate is high (25-50%)
        • incidence of port site incisional hernias is between 1-6%
        • improved trocars and methods of suturing port sites have reduced the chance of herniation
        Risk factors:
        • obesity
        • wound infection
        • smoking
        • diabetes
        • poor nutritional state
        • previous poor surgical closure

        Reducible or irreducible non-tender

        Refer to surgery

        Irreducible and tender and/or obstructed and/or strangulated

        Urgent referral to surgery

        Surgical repair


        • there are various methods of repairing incisional hernias
        • hernias less than 3cm may be repaired by primary tissue approximation
        • larger hernias will require the use of a prosthetic mesh for tension free repair
        • mesh application includes:
          • onlay
          • inlay
          • preperitoneal (sublay) - the preferred location for mesh placement
          • intraperitoneal
        • tissue release techniques, such as component separation, use of tissue flaps, and the application of tissue expansion techniques may obviate the need for prosthetic repair
        • consider laparoscopic repair (intraperitoneal mesh often with an anti-adhesive layer incorporated)

          Umbilical or para-umbilical hernia

          • umbilical hernia in children:
            • a congenital hernia defect caused by the incomplete closure of the umbilical ring (muscle)
            • often asymptomatic but can lead to obstruction and/or strangulation
            • rare in children over age 3 years
            • more common in Afro-Caribbean children
            • more than 90% resolve spontaneously as the abdominal wall matures

            Under age 3 years

            • the majority of umbilical hernias close spontaneously by age 3 or 4 years
            Asymptomatic
            Review at age 3 years

            Symptomatic (reducible)


            • a hernia that reduces spontaneously or with encouragement from the examiner or patient
            Refer to paediatric surgery

            Symptomatic (tender and/or irreducible)


            • irreducible (also described as incarcerated):
              • sac contents do not return to abdominal cavity
            • signs and symptoms of intestinal obstruction:
              • colicky abdominal pain
              • vomiting
              • abdominal distension
              • absolute constipation

              Over age 3 years

              • the majority of umbilical hernias should have closed spontaneously by age 3 or 4 years
              Refer to paediatric surgery

            • para-umbilical hernia in adults:
              • para-umbilical hernias do not occur through the umbilical scar but rather above, or less frequently below, the umbilicus
              • tend to increase in size if untreated
              • obese patients should be encouraged to lose weight
              • a narrow hernia neck is prone to obstruction or strangulation

              Reducible or irreducible non-tender

               Refer to surgery

              Obstructed and/or strangulated

              Refer urgently to surgery

                Inguinal hernia

              • protrusion of a peritoneal sac through the anterior abdominal wall in the groin
              • patients may present with complications of groin hernias, such as incarceration or strangulation of the bowel
              • associated with vague groin pain exacerbated by straining and physical activity
              • surgical referral is recommended
              Classification:
              • indirect:
                • originate lateral to the inferior epigastric artery and follow the path of the spermatic cord (or round ligament in females) through the internal inguinal ring, and along the inguinal canal into the scrotum passing above and medial to the pubic tubercle through the external inguinal ring (in males)
              • direct:
                • originate medial to the inferior epigastric artery and push through a weakness in the posterior wall of the inguinal canal rather than down the canal itself
              Epidemiology:
              • approximately 0.14% of the population in England was estimated to be affected in 2001-2002
              • this resulted in 70,000 surgical repairs - 62,969 were primary repairs while 4939 were recurrent repairs
              • 4.8% of primary repairs present as an emergency with a complication compared to 8.6% of recurrent hernias
              • more common in males
              Risk factors:
              • age
              • male gender
              • obesity
              • chronic cough
              • heavy lifting
              • prostatism
              • chronic constipation
              Clinical presentation:
              • patients may present with symptomatic or asymptomatic hernias
              • symptoms may be mild including abdominal or groin pain and a mass or bulge
              • examination of the patient is to assess whether the hernia can be reduced and whether it is inguinal or femoral
              • it is unnecessary to differentiate between direct or indirect inguinal hernias as the management is the same
              • assessment should rule out incarceration or strangulation as these are surgical emergencies requiring urgent referral
              • signs and symptoms of strangulation include:
                • irreducible mass which is firm, painful, and tender (erythema over mass in later stages)
                • signs of bowel obstruction
                • fever
                • raised white blood cell (WBC) count

                Reducible

              a hernia that reduces spontaneously or with encouragement from the examiner or patient 

              Conservative management

              • repair of easily reducible direct hernias is not mandatory, especially in the elderly
              • a cross over study of surgical repair compared with truss wearing shows a truss is a poor alternative
              • obese patients should be encouraged to lose weight
              • optimise or treat:
                • prostatism
                • chronic cough
                • constipation 

                Consider referral to surgery

                Irreducible and non-tender

              • irreducible (also described as incarcerated):
                • sac contents do not return to abdominal cavity
                • commonly due to adhesions, secondary to a long standing hernia
                • no evidence of bowel ischaemia or obstruction
                • there is a higher risk of strangulation in irreducible hernias
              • the high incidence of complications and their associated postoperative mortality all point to the importance of prompt elective repair
              • elective repair will depend on whether the patients is fit and well, or at high risk of anaesthetic complications

              Consider referal to surgery

              • recent irreducibility with no signs of obstruction or strangulation needs surgical referral within 2-8 weeks
              • long standing irreducibility with no signs of obstruction or strangulation that has previously been assessed by a surgeon needs a surgical opinion within 3 months

              Irreducible and tender and/or obstructed and/or strangulated

              • these patients may be acutely ill
              • obstructed:
                • irreducible hernia containing bowel but with no interference to blood supply
              • strangulated:
                • obstructed bowel with interference to blood supply
                • often erythema over hernia
                • less than 10% of strangulated hernias occur with no previous history of hernia
                • the policy of elective repairs has possibly reduced the incidence of strangulated hernias, but does not result in gain in life expectancy
              • signs and symptoms of obstruction:
                • colicky abdominal pain
                • vomiting
                • abdominal distension
                • absolute constipation
              • on examination:
                • tender, inflamed irreducible hernia
                • absent cough impulse
              • treat as surgical emergency:
                • nil by mouth
                • intravenous (IV) fluids
                • prepare for theatre

                Refer urgently to surgery

              Emergency operation with resection of any ischaemic sac contents
              Refer to surgery
               Assess hernia type

              Unilateral inguinal hernia


              • suitable for surgery if medically fit
              • the three basic approaches to repair are:
                • open suture repair (using patient's own tissue)
                • open mesh repair (tension free or Lichtenstein repair)
                • laparoscopic repair (requires a general anaesthetic)
              Open suture repair:
              • less effective than open mesh repair or laparoscopic repair in improving clinical outcomes
              Open mesh repair:
              • reduced recurrence rate compared to open suture repair
              Laparoscopic repair:
              • two types - totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP)
              • both associated with reduced pain and time taken to return to normal activity compared with open repair

              Inguino-scrotal hernia


              • suitable for surgery if medically fit
              • warn of risk of testicular atrophy
              • the three basic approaches to repair are:
                • open suture repair (using patient's own tissue)
                • open mesh repair (tension free or Lichtenstein repair)
                • laparoscopic repair (requires a general anaesthetic)
              Open suture repair:
              • less effective than open mesh repair or laparoscopic repair in improving clinical outcomes
              Open mesh repair:
              • reduced recurrence rate compared to open suture repair
              Laparoscopic repair:
              • two types - totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP)
              • both associated with reduced pain and time taken to return to normal activity compared with open repair

              Bilateral inguinal hernia


              • suitable for surgery if medically fit
              • simultaneous repair of bilateral hernias may:
                • reduce operating time
                • save two inpatient hospital days; and
                • allow the patient to return to normal activity earlier
              • not associated with any increase in wound complications or postoperative respiratory problems, but increased chance of postoperative urinary retention
              • the three basic approaches to repair are:
                • open suture repair (using patient's own tissue)
                • open mesh repair (tension free)
                • laparoscopic repair (requires a general anaesthetic)
              Open suture repair:
              • may be less effective than open mesh repair or laparoscopic repair in improving clinical outcomes
              Open mesh repair:
              • may be associated with reduced length of stay compared to open suture repair
              Laparoscopic repair:
              • two types - totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP)
              • both are associated with reduced pain and time taken to return to normal activity compared with open repair

              Recurrent inguinal hernia


              • primary inguinal hernia repair should have a recurrence rate of less than 0.5% at 5 years
              • warn that there is a risk of testicular atrophy
              • the three basic approaches to repair are:
                • open suture repair (using patient's own tissue)
                • open mesh repair (tension free or Lichtenstein repair)
                • laparoscopic repair (requires a general anaesthetic)
              Open suture repair:
              • may be less effective than open mesh repair or transabdominal preperitoneal laparoscopic repair in improving clinical outcomes
              Open mesh repair:
              • may be associated with reduced length of stay compared to open suture repair
              Laparoscopic repair:
              • if the primary surgery was done as an open procedure the laparoscopic approach has the advantage of relatively undisturbed tissue planes
              • two types - totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP)
              • both may be associated with reduced time taken to return to normal activity compared with open repai

                Femoral hernia

                • a protrusion of peritoneum into the potential space of the femoral canal medial to the femoral vessels
                • the hernia occurs below and lateral to the pubic tubercle
                • third most common hernia, making up 10% of groin hernias but accounting for 35-50% of emergency presentations, secondary to incarceration or strangulation
                • this hernia occurs more frequently in females than males (4:1)
                • difficult to diagnose in elderly or obese people
                • not normally associated with a visible or palpable cough impulse
                • early surgical referral is recommended for suspected femoral hernias because of the increased risk of incarceration or strangulation

                Reducible


                • a hernia that reduces spontaneously or with encouragement from the examiner or patient 

                Consider referral to surgery

                Irreducible and/or obstructed and/or strangulated

                • Richter's hernia are relatively common in the femoral sac, as:
                  • they do not contain bowel lumen - symptoms of obstruction will not occur, but bowel wall ischaemia and perforation may

                  Refer urgently to surgery:

                  Surgical repair

                • all patients with femoral hernias should be considered for surgical repair because of the high incidence of bowel strangulation
                • urgent repair is indicated for patients with signs of incarceration or strangulation
                • repair may be carried out under general, regional, or local anaesthetic 
                • the three basic approaches to repair are:
                  • open repair (using patient's own tissue) - three approaches:
                    • low (Lockwood)
                    • inguinal (Lotheissen)
                    • high (McEvedy)
                  • open tension free repair (using a mesh)
                  • laparoscopic repair (requires a general anaesthetic)

                  Lumbar hernia

                  • may appear spontaneously through one or two anatomical points of weakness within the lumbar region:
                    • the lumbar triangle of Petit (bounded by the iliac crest, posterior edge of external oblique and anterior edge of latissimus dorsi)
                    • the superior quadrilateral lumbar space (bounded by the twelfth rib, the lower border of serratus posterior inferior, the anterior border of erector spinae and the internal oblique)
                  • predisposing factors include:
                    • renal operations
                    • lumbar abscess 
                    • paralysis of the lateral lumbar muscles, ie. by poliomyelitis or spina bifida 
                  • the neck of the hernial sac is wide and therefore rarely requires surgery

                  Spigelian hernia

                  • represent less than 1% of all abdominal hernias
                  • occurs through the linea semilunaris at the outer border of the rectus abdominis muscle
                  • occurs below the umbilicus and is more frequent in women than men (1.5:1)
                  • liable to strangulate
                  • can be clinically difficult to diagnose but ultrasound, CT scan, or magnetic resonance imaging (MRI) of the abdominal wall aid in the diagnosis
                  • open repair of the hernia is by excision of the peritoneal sac and closure of the aponeurotic defect
                  • laparoscopic surgery may be diagnostic as well as therapeutic

                  Parastomal hernia

                  • parastomal hernias are a common complication of an ileostomy or colostomy 
                  • symptoms include intermittent bowel obstruction if the hernia contains a segment of bowel proximal to the stoma
                  • rate of occurrence is higher in end ileostomies (1.8-28.3%) compared to loop ileostomies (0-6.2%)
                  • rate of occurrence following colostomies is estimated to be between 4-48.1% (end colostomies) and 0-30.8% (loop colostomies)
                  • there is limited evidence that mesh repair is associated with a lower recurrence rate compared to direct tissue repair or stoma relocation

                   

                الاثنين، 7 فبراير 2011

                Plummer-Vinson syndrome

                 Plummer-Vinson syndrome: "Paterson-Brown-Kelly syndrome



                Some Causes of Esophageal Dysphagia


                Motility disorder
                • Achalasia
                • Diffuse esophageal spasm
                • Systemic sclerosis
                • Eosinophilic esophagitis

                Mechanical obstruction
                • Peptic stricture
                • Esophageal cancer
                • Lower esophageal rings
                • Extrinsic compression (eg, from enlarged L atrium, aortic aneurysm, aberrant subclavian artery [termed dysphagia lusoria], substernal thyroid, cervical bony exostosis, and thoracic tumor)
                • Caustic ingestion

                السبت، 5 فبراير 2011

                TREATMENT OF THE ACUTE ABDOMEN

                Most students learn each topic as it is laid out in the textbooks. However,
                in real life a patient does not present saying ‘I have acute appendicitis’,
                and neither does he always present with the classical textbook description.
                Instead, most patients tend to present with a variety of vague symptoms
                and signs that do not point to any specific diagnosis. The acute abdomen
                is the best topic for highlighting this fact, because a patient who presents
                with epigastric pain and vomiting could be having pancreatitis, cholecys-
                titis, a perforated peptic ulcer or just gastritis, and it may not be possible
                to differentiate on the history alone. The examination and simple investi-
                gations add further clues to help make a diagnosis, but still it may not be
                possible to make an absolute diagnosis initially and management may
                consist of simple treatment such as resuscitation, analgesia and a period
                of observation whilst further investigations are performed. In other cases,
                although a specific diagnosis is not made, exploratory laparotomy may be
                needed (i.e. in cases of generalised peritonitis).

                 
                As a student, making the wrong diagnosis is not that important,
                because there will always be a doctor available to correct you. As a doctor,
                however, you need to ask yourself ‘What if I am wrong?’ with each deci-
                sion made. Performing an appendicectomy on a patient with mesentericadenitis is
                unlikely to be life-threatening; on the other hand, if you make a
                diagnosis of acute appendicitis in a female with right-sided pain without
                first performing a pregnancy test, then the surgeon may be left with an
                appendicectomy incision to deal with an ectopic pregnancy. For example,
                let us say a 14-year-old girl presents with right iliac fossa pain and nausea.
                The possible causes of this are appendicitis, mesenteric adenitis, a UTI, an
                ectopic pregnancy or any other gynaecological problem, or even just wind.

                 
                You should, therefore, ask not only the pertinent questions that point to a specific  
                diagnosis but also the questions that will rule out the other diagnoses. Thus, note the
                menstrual history and the history of the pain; for example, the pain of appendicitis 
                usually starts centrally and moves to the right side after a few hours, whereas a torsion
                of an ovarian cyst gives a sudden onset of right iliac fossa pain. A UTI usually has 
                associated urinary symptoms (frequency, dysuria and urgency).

                 
                Next, you derive further clues from the examination, looking for
                localised right iliac fossa tenderness or peritonism. Further clues are again
                derived from the simple investigations. A pregnancy test and urine dipstix
                and urgent microscopy must be performed to rule out an infection. A sim-
                ple blood test such as a white cell count may help (although it is not that
                specific), and plain X-rays may give further clues (although not that help-
                ful in this case, they would be if renal stones or bowel obstruction were on
                the differential).

                 
                At this point you may have narrowed the differential down to appendicitis
                mesenteric adenitis or a gynaecological problem, but you still may not be exactly
                sure which it is. It is safe then to admit the patient, start IV fluids and carefully
                observe her with repeated examinations. If the pain and tenderness appear to settle,
                no further treatment may be necessary.

                However, if they persist, then it may be necessary to investigate the
                patient further. An ultrasound can be helpful, as it can visualise the
                ovaries and look for any free fluid. It may even show up an enlarged
                appendix. In this situation an ultrasound is very sensitive although not
                that specific, and even if it shows no abormality it does not rule out
                appendicitis. Another option is to perform a diagnostic laparoscopy
                where the organs are visualised directly via a laparascope. If the appen-
                dix is inflamed it could be removed laparascopically (if the surgeon has
                 
                enough experience) or conversion to an open procedure can take
                place. In a male with the same history, symptoms and signs there is
                not much else it can be apart from appendicitis and mesenteric adenitis,
                and if the pain did not settle after a period of observation many surgeons 
                would agree that an appendicectomy was indicated without any further
                investigation.

                EXAMINATION OF PATIENT WITH ACUTE ABDOMEN

                Obviously, it is always important to do a general examination of the
                patient. In particular, attention should be paid to signs of shock or dehy-
                dration as manifested by peripheral shut-down, clamminess, pallor, tachy-
                cardia and hypotension. One can often tell, just by looking at the patient,
                whether he is unwell. The typical patient with peritonitis looks pale and
                sweaty, with sunken eyes and a weak thready pulse, shallow breaths and
                little movement — as first described by Hippocrates thousands of years ago.


                Introduce yourself to the patient, ask if he minds your examining him
                and if he has any pain. Lay him flat (one pillow) and adequately undress
                him (ideally from nipples to knees, but in the exam you should try to pre-
                serve the patient’ s dignity). On inspection of the abdomen (from the foot
                of the bed) observe for any obvious scars or masses, distension and the
                movement with respiration. You may find it easier in an exam situation to
                comment on your observations as you go along (unless you are confi-
                dent you can present it all at the end). It is sometimes difficult to differ-
                entiate fat from distension (which can be due to flatus or fluid or foetus
                or faeces)



                Next, hold the hand and look for any nail changes (e.g. clubbing), liver palms, etc.,
                feel the pulse, look into the mouth for furring of the tongue and for dry mucous
                membranes, look into the eyes for jaundice or anaemia (pale conjunctiva) and
                swiftly feel the neck for any lymph nodes.


                On palpation of the abdomen (make sure the hands are warm) kneel
                down to the patient’ s right, so that you are roughly level with him. The
                abdomen can be divided into theoretical regions.

                Starting at the furthest point from where he tells you the pain is, gently feel in each
                of these regions. This gives you a quick idea of any obvious masses or
                tender areas and whether the abdomen is soft. You should begin to think
                of what anatomical structures are under this area. Always look up at the
                patient’ s face (for grimacing). Next you can palpate a little deeper to build
                up on the findings of gentle palpation. Note if there is any guarding, rigidity
                or rebound. Rebound tenderness (most painful when the examining hand
                is removed) is not a good test, as it often causes the patient unnecessary
                pain and can give equivocal results. Tenderness on percussion is a more
                accurate and kinder way of assessing the same thing.


                Examine the liver and spleen (starting in the right iliac fossa for both,with the patient inspiring each time you press in). In right upper quadrant abdominal pain, Murphy’ s test for cholecystitis is relevant, and if any masses or enlarged organs are palpated then the precise features need to be delineated. After palpation, percussion should be used before auscultation. Bowel sounds should be classified as being present (i.e. normal), absent (must listen for 3min) or obstructive (high-pitched and tinkling).


                Always finish your examination by palpating for an abdominal aortic aneurysm and check the 
                hernial orificesand scrotum. A rectal examination is mandatory (although in an exam you usually 
                just state that you would like to do it). The breast is really part of the abdominal examination, 
                since if you were shown a case of  ascites in the exam and you did not comment on the mastectomy 
                scar, you would not receive any bonus points!


                Peritonitis


                Peritonitis means inflammation of the peritoneum.

                In contrast to visceral pain, the parietal peritoneum is innervated by somatic nerves and
                hence pain is accurately localised to the site of inflammation. 

                This type of pain is typically worse with movement, coughing or inspiration and therefore 
                the patient lies still with shallow breaths (unlike colicky pain, where he moves about to try 
                to get comfortable).
                Peritonitis is associated with guarding or rigidity of the abdominal muscles.
                There appears to be some difference in opinion as to the true definition of guarding and
                rigidity; however, most surgeons would agree that guarding is an involuntary (reflex) 
                contraction  of the abdominal muscles when the examining hand presses down over the inflamed area. 

                 It is sometimes difficult to differentiate true guarding from voluntary guarding, where the
                patient contracts his own abdominal muscles in anticipation of pain (especially seen
                in children). However, if you palpate the two sides of the abdomen at thesame time while 
                distracting the patient, you may find that the muscles appear tense on one side compared to
                the other. It is not really possible to do this voluntarily (where the two sides contract 
                symmetrically) and hence this must be true guarding. If at rest the patient’ s abdominal 
                musculature has an increased tone, then this is termed rigidity and is again due to
                underlying inflammation of the peritoneum. If peritonitis involves thewhole abdomen, then 
                the patient would typically present with a boardlike, rigid, tender abdomen with absent bowel sounds.

                WOUND INFECTIONS

                Incidence:
                • Third most frequently reported nosocomial infection
                • Culprits: S. aureus (20%), E. coli (10%), Enterococcus (10%), S. epidermidis,
                Pseudomonas, Streptococcus, other anaerobes


                Degree of Intraoperative Contamination:
                1. Clean: no gross contamination from endogenous or exogenous sources, e.g. skin
                or vascular cases
                • Infection rate about 1.5-5%
                2. Clean-contaminated: lightly contaminated, e.g. gastric or biliary cases, GU, gyn,
                respiratory tract surgery
                • Infection rate about 3-7% if prophylactic antibiotics used
                3. Contaminated: heavily contaminated, e.g. penetrating trauma, bowel spillage,
                operations on unprepared colon
                • Infection rate about 10-15%
                4. Infected: e.g. gross pus, gangrene, bowel perforation encountered
                • Infection rate 15-40%
                Patient characteristics:
                1. Diabetes mellitus, uremia, extremes of age, immunosuppression
                2. Decreased blood flow to wound: hypoxemia, nicotine
                3. Malnutrition: protein depletion
                4. Injury: irradiated or devitalized tissue
                5. Foreign body
                Prevention: CDC recommendations
                1. Careful, clean, gentle surgery, minimizing tissue trauma, wound hematomas,
                number of ligatures, and drying or pressure from retractors
                2. Reduction of contamination
                3. Support of patient’s defenses, including prophylactic antibiotics: indicated when
                wound contamination during operation likely to be high (contaminated).
                Antibiotics not shown to reduce incidence of wound infections after clean
                operations.
                Treatment:

                1. Open the wound and allow it to drain.
                2. Perform digital exam to assess for fascial dehiscence.
                3. Antibiotics indicated if patient immunocompromised, if prosthetics involved, if
                patient has signs of systemic toxicity or if surrounding area of soft tissue
                erythema and edema
                4. Cultures should be performed in case existing infection becomes invasive.


                Curveballs:
                1. Ascites
                • Patients with ascites at risk of fluid leak through wound, with higher incidence
                of wound infections and risk of peritonitis through retrograde contamination.
                Prevention involves closing at least one layer with a continuous suture and
                preventing accumulation of ascites postoperatively
                2. Burns
                • S. aureus: Slow onset over 2-5 days; marked increase in temperature and
                leukocytosis; mortality approx 5%
                • P. aeruginosa: Rapid onset over 12-36 hours; high or low temp and WBC;
                often severe hypotension; mortality approx 20-30%
                3. Diffuse necrotizing infections
                • Clinical findings: High fever POD #1 - wound needs immediate inspection for
                crepitance or air bubbles on xray, cellulitis or skin discoloration
                • Nonclostridial: More common in diabetics; causal organisms are anaerobic
                Streptococci, Staphylococci, and Bacteroides; clinical findings erythema,
                edema beyond erythema, crepitance, sepsis
                • Clostridial myonecrosis: bronze-brown seropurulent weeping exudates and
                mousy odor characteristic of Clostridia perfringens (80% of cases of tissue
                necrosis; creates exotoxins which destroy microcirculation allowing rapid
                advancement of infection)
                • Treatment: emergent aggressive wide debridement and broad-spectrum
                antibiotics (IV high-dose Penicillin for Clostridia)




                References:
                • Malone, D. et al. Surgical Site Infections: Reanalysis of Risk Factors. J of Surgical
                Research 2002; 103: 89-95.
                • Taylor, E. et al. Surgical site infection after groin hernia repair. British J of Surgery
                2004; 91: 105-111.
                • Culver DH et al. Surgical wound infection rates be wound class, operative procedure,
                and patient risk index. National Nosocomial Infection Surveillance System. Am J
                Med 1991; 91: 152S.
                • Way, Larry. Current Surgical Diagnosis and Treatment, 11th Ed, 2003
                • Mont Reid Surgical Handbook, 4th Ed, 1997
                • CDC/USDHHS guideline for prevention of surgical site infection, 1999



                Philippa Newell, M.D.
                April 1, 2004



                Lower GI bleeding workup